Seeing what the body says.

A living, intelligent system.

Interstitial fluid surrounds every cell in the body. It carries critical information — including biomarkers tied to inflammation, immune function, and metabolic activity. It’s the biological layer where changes begin.

Learn more about ISF.

Until now, accessing ISF has required invasive procedures or unreliable methods.

KIFFIK changes that with a patented, point-of-care technology that extracts ISF safely, gently, and without pain.

How it works.

It's fast.

It's easy to use.

It's non-invasive.

Our proprietary device uses a brief, controlled electrical pulse — a method known as electroporation — to create temporary microchannels in the outer skin. This opens a  pathway to interstitial fluid, without needles or blood. 

Electroporation

Extraction

How the KIFFIK Lab works.

From micro-pulse to biomarker access —
see how KIFFIK’s technology works.
The KIFFIK device is unique in generating high-quality ISF samples. The generated samples can be extremely valuable for clinical applications such as faster, easier recruitment of clinical trials, biomarker research and development, assessment of disease mechanisms, for new drug targets, drug repurposing and new combination therapies.”
Ronny Schmidt, PhD
VP Contract Research, Sciomics, GmbH

A deeper dive.

Want to learn more?

interstitial fluid

The following peer-reviewed references highlight the clinical and scientific foundation for using interstitial fluid (ISF) as a biomarker-rich biofluid for diagnostics, wearable monitoring, and future applications in precision health.

ELECTROPORATION

Electroporation has emerged as a promising method for non-invasive access to interstitial fluid (ISF), enabling wearable diagnostics and continuous biomarker monitoring. The following references provide foundational scientific and clinical insights into the use of electroporation to enhance ISF sampling.